MME

MME, also known as Membrane Metallo-Endopeptidase or neprilysin, is a zinc-dependent metalloprotease enzyme that plays a crucial role in regulating peptide signaling molecules. It is primarily found on the cell membranes of various cell types, including neurons, endothelial cells, and immune cells. MME is especially important for breaking down peptides involved in blood pressure regulation, such as bradykinin and atrial natriuretic peptide (ANP), converting them into inactive fragments and helping maintain cardiovascular balance.