Free Cortisol refers to the unbound, biologically active form of cortisol circulating in the body. Unlike total cortisol, which includes both bound and unbound hormone, free cortisol represents the fraction that is available to tissues and can directly influence stress response, metabolism, immune function, and energy levels. Measuring free cortisol provides a more accurate reflection of how the body is responding to physical and emotional stress. It is commonly assessed in urine or saliva samples and is particularly relevant in evaluating adrenal function and circadian rhythm imbalances.

Individuals experiencing chronic stress, fatigue, anxiety, or symptoms of adrenal dysfunction would benefit from cortisol testing. It’s also helpful for those with irregular sleep patterns, weight changes, or ongoing health issues linked to stress.
High Cortisol:
Low Cortisol:
Saliva testing for cortisol measures free, active hormone levels, reflecting the body’s immediate response to stress. Blood tests measure total cortisol, including both bound and unbound cortisol, giving a broader view of adrenal function over time.
Cortisol levels fluctuate throughout the day, peaking in the morning and gradually declining. Measuring several times captures this natural rhythm, providing a more accurate assessment of adrenal function and stress response.
Lab Test
Saliva
This at-home adrenal test, which consists of two separate tests for cortisol and DHEA via saliva, analyzes adrenal insufficiency or hormone imbalance. Such imbalances can lead to typical symptoms of adrenal fatigue, including fatigue or exhaustion, sleep disturbances, salt cravings, and low blood pressure.
Additionally, it is popular to combine this test with either our Estrogen/Progesterone Test or Testosterone Test for a more comprehensive hormonal assessment.
$ 149.99 USD
Add to cartLab Test
Saliva
GetTested’s Cortisol Test measures bioavailable and free cortisol on seven occasions during a day. Cortisol is released in response to physical or mental stress. Produced by the adrenal glands, cortisol boosts physical and mental performance under short-term stress. However, consistently high cortisol levels can harm your health, while too low levels can also be problematic. This test is particularly useful for individuals experiencing chronic stress, fatigue, or other stress-related symptoms.
Additionally, DHEA, another hormone influenced by stress, is commonly measured alongside cortisol for a comprehensive hormonal assessment. Our DHEA Saliva Test can further enhance understanding of your stress response and hormonal balance.
$ 69.99 USD
Read MoreLab Test
Saliva
Men’s Hormone Test by GetTested, is for those seeking an in-depth understanding of their hormonal health. This saliva-based test analyzes key hormones such as testosterone, DHEA, cortisol, estrogen, and progesterone. Tailored for men, it offers crucial insights into both sex hormones and adrenal hormones. Understanding these hormone levels can be vital in assessing various health aspects, including energy levels, mood stability, and overall physical well-being.
For those looking to further enhance their health screening, our PSA Test, available as both a rapid and laboratory test, is another popular option among men for monitoring prostate health.
$ 189.99 USD
Add to cartLab Test
Saliva
Women’s Hormone Test analyses cortisol, estrogen, progesterone, testosterone, DHEA, and the ratio between estrogen and progesterone. Many women today face challenges with PMS, infertility, fatigue, irregular periods, PCOS, menopausal symptoms, and more. This test offers a detailed understanding of both your sex hormones and adrenal hormones, providing insights into various health issues.
Additionally, if you are experiencing mood issues, we recommend our Neurotransmitters Basic or Plus tests, which measure levels of key neurotransmitters such as serotonin and dopamine, to further explore potential imbalances affecting your well-being.
$ 159.99 USD
Read More