Asparagus intolerance is a condition where individuals have trouble digesting asparagus, leading to gastrointestinal discomfort. Unlike an asparagus allergy, which triggers an immune response and can cause more severe reactions, asparagus intolerance usually results in digestive symptoms after eating it.

TMEM171 (Transmembrane Protein 171): TMEM171 is a gene that encodes a transmembrane protein. Although its specific functions are not yet fully known, transmembrane proteins typically play key roles in cell signaling, molecule transport across membranes, and cellular communication. Additional research is necessary to determine the exact functions of TMEM171 in cellular processes.

MME, also known as Membrane Metallo-Endopeptidase or neprilysin, is a zinc-dependent metalloprotease enzyme that plays a crucial role in regulating peptide signaling molecules. It is primarily found on the cell membranes of various cell types, including neurons, endothelial cells, and immune cells. MME is especially important for breaking down peptides involved in blood pressure regulation, such as bradykinin and atrial natriuretic peptide (ANP), converting them into inactive fragments and helping maintain cardiovascular balance.

MITF (Melanocyte Inducing Transcription Factor): MITF is a key regulator that highlights its role in the development and function of melanocytes, the cells responsible for pigment production. It is essential for normal pigmentation, and mutations in MITF can cause pigmentary disorders and raise the risk of melanoma, a type of skin cancer. MITF also plays a role in the development of certain retinal cells and is linked to Waardenburg syndrome.

TRIB1 (Tribbles Pseudokinase 1): TRIB1 is a gene that encodes a pseudokinase protein in the Tribbles family. TRIB1 plays essential roles in regulating various cellular signaling pathways, including those related to growth, metabolism, and inflammation. It is associated with lipid metabolism, cardiovascular health, and cancer, with its complex functions remaining a significant focus of ongoing research.

Taurine is an amino acid essential for the function of heart muscles, vision, and nerve health. It supports cardiovascular health, helps maintain healthy eyes, and aids in nerve growth and activity. Taurine naturally occurs in foods like meat, fish, and dairy.

LRFN5 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 5): LRFN5 is a member of the LRFN protein family. It plays a role in neuronal development and synaptic function, contributing to the formation and maintenance of neural circuits. Abnormalities in LRFN5 may be linked to neurodevelopmental disorders.

RBPJ (Recombination Signal Binding Protein for Immunoglobulin Kappa J Region): RBPJ is a key transcription factor in the Notch signaling pathway, which plays a critical role in regulating cell fate, differentiation, and development. Proper function of RBPJ is essential for tissue development and cell specialization, while dysregulation of RBPJ and Notch signaling is linked to various diseases, including cancers and developmental disorders.

Tryptophan is an essential amino acid that supports sleep and mood. It helps the body produce serotonin, a neurotransmitter that affects sleep, emotions, and appetite. Found in foods like turkey, chicken, milk, and nuts, tryptophan plays a vital role in relaxation, sleep, and overall mental well-being.

TWIST1 (Twist Family BHLH Transcription Factor 1): TWIST1 is a gene that encodes a protein essential for embryonic development, particularly in directing mesenchymal cell lineage determination. It plays a role in craniofacial development and is linked to Saethre-Chotzen syndrome — a congenital disorder characterized by craniosynostosis.

NCOR1 (Nuclear Receptor Corepressor 1) is a protein that plays a crucial role in regulating gene expression and transcriptional repression. Primarily located in the cell nucleus, NCOR1 modulates the activity of nuclear receptors and other transcription factors. It serves as a corepressor for receptors such as thyroid hormone receptors (TRs), retinoic acid receptors (RARs), and peroxisome proliferator-activated receptors (PPARs). By recruiting histone deacetylases (HDACs) and other chromatin-modifying enzymes, NCOR1 helps establish repressive chromatin structures, leading to decreased gene transcription.

Mussels intolerance is a condition where the body struggles to digest mussels, often leading to gastrointestinal discomfort. It is different from a mussels allergy, which involves an immune system response and can cause more severe symptoms. People with mussels intolerance usually experience digestive problems after eating this type of shellfish.

KCTD1 (Potassium Channel Tetramerization Domain Containing 1): KCTD1 is a protein that interacts with potassium channels, affecting their activity. It plays key roles in cellular functions such as signal transduction and ion transport. Mutations in KCTD1 have been linked to developmental disorders, especially those impacting skin and hair.

Palladium is a metal used in electronics, jewelry, and dental materials. While it is useful across various industries, high levels of inhalation or ingestion can be toxic, especially in occupational settings. Exposure may cause respiratory, skin, and digestive problems, and some individuals may develop allergic reactions such as dermatitis.

SCARB1 (Scavenger Receptor Class B Member 1): SCARB1 is a protein that plays a key role in the selective uptake of cholesterol esters from high-density lipoprotein (HDL) particles. It is essential for lipid metabolism and reverse cholesterol transport. Variants in SCARB1 can affect cholesterol levels and have been linked to cardiovascular disease risk.

APEH (Acylaminoacyl-Peptide Hydrolase): APEH is an enzyme that plays a crucial role in protein turnover by breaking down acetylated peptides. It participates in processing damaged or misfolded proteins, helping to maintain protein balance. Malfunctions in APEH can affect neurodegenerative processes and the body's ability to respond to oxidative stress.

GPR139 is a G protein-coupled receptor (GPCR) primarily found in the central nervous system, especially in areas involved in regulating neurotransmitter systems and neuronal activity. It is believed to modulate neurotransmission, particularly dopamine and glutamate signaling, and may function as an inhibitory receptor by decreasing cAMP levels and lowering neuronal excitability.

Baker’s yeast intolerance is a condition where individuals have trouble digesting baker’s yeast, often leading to gastrointestinal discomfort. Unlike a baker’s yeast allergy, which triggers an immune response and can cause more severe reactions, intolerance is limited to digestive problems. Symptoms usually appear after consuming foods or beverages made with baker’s yeast.

SLC22A5 (Solute Carrier Family 22 Member 5): SLC22A5 is a protein, also known as OCTN2, that acts as a primary carnitine transporter in the body. It enables the cellular uptake of carnitine, a molecule essential for transporting fatty acids into mitochondria for energy production. This process is crucial for energy metabolism in tissues such as the heart and muscles. Mutations in the SLC22A5 gene can cause primary carnitine deficiency, a disorder characterized by muscle weakness and cardiomyopathy, underscoring its important role in metabolic health and energy regulation.

The quantitative determination of nitrogen (N) is a laboratory test that measures nitrogen levels in bodily excretions, typically urine or feces, to evaluate protein digestion and absorption. This test is crucial for assessing nutritional status, especially in clinical settings where protein-energy malnutrition or imbalances may be a concern. It offers important insights into metabolic functions related to protein turnover and can help diagnose conditions affecting protein metabolism, including kidney disease, malabsorption syndromes, and certain metabolic disorders.

COL11A1 (Collagen Type XI Alpha 1 Chain): COL11A1 is a gene that encodes a crucial component of type XI collagen, which is vital for the structure and integrity of connective tissue. Mutations in COL11A1 are associated with several connective tissue disorders, including certain forms of Ehlers-Danlos syndrome and Stickler syndrome.

Chicken intolerance is a condition where the body struggles to digest chicken, causing digestive discomfort. Unlike a chicken allergy, which triggers an immune response and can lead to immediate and severe reactions, chicken intolerance usually results in gastrointestinal symptoms after eating chicken.

SCAMP1 (Secretory Carrier Membrane Protein 1): SCAMP1 is a protein involved in membrane trafficking processes, especially in the recycling of membrane proteins and in exocytosis. It plays a crucial role in cellular communication and the transport of substances within cells, which is vital for various cellular functions.

THADA (Thyroid Adenoma Associated): THADA is a gene linked to thyroid adenomas, a type of thyroid tumor. It may contribute to the development of thyroid tumors and has been associated with thyroid cancer progression, making it a key focus of ongoing research in thyroid diseases.

Grape intolerance is a condition where the body struggles to digest grapes, causing gastrointestinal discomfort. Unlike a grape allergy, which triggers an immune response and can lead to severe reactions, grape intolerance generally causes digestive symptoms after eating grapes or products made from grapes.

PKP4 (Plakophilin 4): PKP4 is a protein that supports cell-to-cell adhesion, especially within desmosomes — specialized structures that connect neighboring cells. It helps maintain tissue integrity, particularly in areas subjected to mechanical stress. Mutations in PKP4 can impair this function, leading to certain skin and heart disorders.

Grass pollen allergies indicate sensitivity to various types of grass—including sweet vernal, orchard grass, common reed, and bent grass. These allergens can significantly impact individuals who are prone to allergic reactions, affecting respiratory health, causing eye irritation, and reducing overall well-being. Understanding these allergies, recognizing the symptoms, and using effective management strategies can help lessen discomfort and enhance quality of life during peak pollen seasons.

Dermatophagoides pteronyssinus (D. pteronyssinus), commonly known as the European house dust mite, is a common indoor allergen. These microscopic organisms thrive in warm, humid environments and feed on organic matter such as shed human skin flakes. Their body fragments and waste products can trigger allergic reactions and asthma in sensitive individuals.

SERTAD2 (SERTA Domain Containing 2): SERTAD2 is a multifunctional protein that contains a SERTA domain, which is associated with cell cycle regulation. Beyond its role in cell cycle progression, SERTAD2 is involved in essential cellular processes such as DNA replication, DNA repair, and chromatin remodeling. Its interactions with various transcription factors and co-regulators establish it as a key regulator of gene expression.

HPRT1 (Hypoxanthine Phosphoribosyltransferase 1): HPRT1 is a crucial gene involved in purine metabolism. It catalyzes the conversion of hypoxanthine into inosine monophosphate (IMP), a key precursor for purine nucleotide synthesis. Mutations in HPRT1 can lead to Lesch-Nyhan syndrome, a rare genetic disorder characterized by neurological and behavioral abnormalities.

Kynurenine is a key metabolite in the breakdown of the essential amino acid tryptophan. It serves as a precursor to several important compounds, including the neuroprotective kynurenic acid and the neurotoxic quinolinic acid, and plays a crucial role in various physiological and pathological processes in the body.

HORMAD1 (HORMA Domain-Containing Protein 1): HORMAD1 is a gene that encodes a protein with a HORMA domain, which plays a role in chromosome dynamics during meiosis. It is essential for regulating homologous chromosome pairing and segregation, supporting genetic diversity and proper gamete formation.

Lamb intolerance is a condition where the body struggles to digest lamb meat, causing gastrointestinal discomfort. Unlike a lamb allergy, which triggers an immune response and can lead to severe symptoms, lamb intolerance typically results in digestive problems that occur after eating lamb.

Urine density, also known as urine specific gravity, measures the concentration of solutes in urine. It indicates the kidney’s ability to concentrate or dilute urine and serves as a marker of hydration status and kidney function. Although normal values can vary, abnormalities may signal dehydration, overhydration, or underlying kidney conditions.

ATP1B3 (ATPase Na⁺/K⁺ Transporting Subunit Beta 3): ATP1B3 is a component of the Na⁺/K⁺ ATPase pump that maintains cellular ion gradients essential for regulating cell volume and electrical activity. This subunit affects the pump’s activity and specificity, supporting muscle function, nerve signaling, and kidney filtration. Changes in ATP1B3 may be associated with cardiovascular and neurological disorders.

Beef intolerance is a condition where the digestive system reacts negatively to eating beef. Unlike a beef allergy, which causes an immune response and can be more serious, beef intolerance involves difficulty digesting or processing certain parts of beef.

Yolk intolerance, specifically concerning egg yolks, is a condition where individuals have difficulty digesting egg yolks, leading to gastrointestinal discomfort. This intolerance is distinct from an egg allergy, which involves an immune system response to egg proteins and can cause more severe reactions. Yolk intolerance typically results in digestive symptoms following the consumption of egg yolks....

Dill intolerance is a condition where individuals have trouble digesting dill, an herb commonly used for its unique flavor in pickles, salads, and seafood dishes. It usually causes gastrointestinal discomfort and is different from a dill allergy, which triggers an immune response and can lead to more severe symptoms. People with dill intolerance typically experience digestive problems after eating dill or foods that contain it.

Pinworms (Oxyuris), also known as threadworms, are common intestinal parasites, especially in children. These small, white worms cause itching around the anus, disrupted sleep, and irritability due to their nighttime egg-laying. Infection spreads through the fecal-oral route, often by ingesting microscopic eggs from contaminated hands, surfaces, or food.

King crab, a highly prized delicacy in seafood cuisine, is appreciated for its rich flavor and tender texture. However, some people may have an intolerance to king crab, which can restrict their ability to enjoy this seafood.

New World hookworms (Necator americanus) are parasitic worms commonly found in the Americas. These parasites attach to the intestinal walls of their hosts, leading to chronic blood loss, anemia, and protein deficiency. The larvae can penetrate the skin from contaminated soil, putting individuals who come into contact with such environments at risk of infection.

Threadworms (Strongyloides stercoralis) are tiny intestinal parasites that cause strongyloidiasis. They can be asymptomatic or cause various symptoms, including abdominal pain, diarrhea, and, in severe cases, malabsorption. Transmission occurs through skin contact with contaminated soil. These worms are notable for their ability to reproduce within the host, leading to persistent, long-lasting infections.

Tapeworms are intestinal parasites that can infect both humans and animals. These flat, segmented worms can grow to significant lengths. They usually enter the body through eating contaminated food or drinking contaminated water. While tapeworm infections can sometimes show no symptoms, they may also cause abdominal pain, diarrhea, and weight loss.

Fennel intolerance is a condition in which the body has trouble digesting fennel, an aromatic herb commonly used in Mediterranean and Indian cooking. It usually causes gastrointestinal discomfort and is different from a fennel allergy, which involves an immune response and can lead to more serious symptoms. People with fennel intolerance typically experience digestive problems after eating fennel or foods flavored with fennel.

Ureaplasma is a group of tiny bacteria commonly found in the urogenital tracts of both men and women. They are part of the normal genital flora but can cause infections under certain conditions. Ureaplasma species, especially Ureaplasma urealyticum and Ureaplasma parvum, are linked to conditions such as urethritis, pelvic inflammatory disease (PID), and infertility. While they can be sexually transmitted, they are not always strictly classified as STIs.

Avocado intolerance is a condition where individuals experience difficulty digesting avocado, often leading to gastrointestinal discomfort. Unlike an avocado allergy, which triggers an immune system response and can cause more severe reactions, avocado intolerance is limited to digestive symptoms that occur after eating avocado.

Honey intolerance is a condition where individuals have trouble digesting honey, a natural sweetener made by bees. It can lead to gastrointestinal discomfort and is different from a honey allergy, which involves an immune response and can cause more serious symptoms. People with honey intolerance usually experience digestive problems after eating honey or products that contain it.

Chamomile tea intolerance is a condition characterized by difficulty digesting chamomile tea, an herbal infusion made from dried chamomile flowers. Unlike a chamomile tea allergy, which triggers an immune response and can cause more severe reactions, intolerance primarily causes digestive discomfort. People with chamomile tea intolerance usually experience gastrointestinal symptoms after drinking chamomile tea.

Eggplant intolerance, also known as aubergine intolerance in some regions, is a condition characterized by difficulty digesting eggplant. Unlike an eggplant allergy, which involves an immune system reaction and can cause more severe symptoms, intolerance mainly results in gastrointestinal discomfort. Individuals with eggplant intolerance usually experience digestive issues after eating eggplant.

Cabbage intolerance refers to difficulty digesting cabbage, often causing gastrointestinal discomfort. Unlike a cabbage allergy, which triggers an immune response, this intolerance is related to digestion and usually leads to symptoms after consuming cabbage.

Herring intolerance is a condition where the body struggles to digest herring, often resulting in gastrointestinal discomfort. Unlike a herring allergy, which triggers an immune response and can lead to severe reactions, herring intolerance usually causes only digestive symptoms after consuming this type of fish.

Acarus siro, commonly known as the flour mite, is a species frequently found in stored grains and flour. These mites can thrive in kitchen cupboards and pantries, especially in humid environments. For sensitive individuals, exposure may cause allergic reactions and can be particularly problematic for those with preexisting respiratory issues.

LDL (Low-Density Lipoprotein) is a type of cholesterol often called “bad” cholesterol. It transports cholesterol particles through the bloodstream, and elevated levels can lead to plaque buildup in the arteries. This buildup, known as atherosclerosis, can narrow and harden the arteries, increasing the risk of heart disease and stroke.

AHSG (Alpha-2-HS-Glycoprotein), also known as fetuin-A, is a glycoprotein involved in various physiological processes, including the inhibition of mineralization and the regulation of insulin sensitivity. Elevated AHSG levels have been associated with insulin resistance and metabolic syndrome, indicating its potential as a biomarker for these conditions.

Rye intolerance is a condition where the body struggles to digest rye, causing gastrointestinal discomfort. Unlike a rye allergy, which triggers an immune response and can lead to more severe symptoms, rye intolerance usually results in digestive problems after eating rye or rye-based products.

ATP8B1 (ATPase Phospholipid Transporting 8B1) is a gene that encodes a phospholipid transporter located in the liver cell membrane. It plays a role in maintaining the lipid balance of cell membranes and bile. Mutations in ATP8B1 can cause progressive familial intrahepatic cholestasis (PFIC), a group of inherited liver disorders.

Shrimp allergy is a common shellfish allergy caused by an immune reaction to proteins found in shrimp. It is one of the most common food allergies in adults and can cause symptoms ranging from mild to severe, including anaphylaxis. This allergy is typically lifelong and may be triggered by eating shrimp or even inhaling steam while cooking.

Urinary leukocytes are white blood cells found in urine. They are usually absent or present in very small amounts, and elevated levels often indicate infection or inflammation in the urinary tract or kidneys. Detecting them is an important indicator for diagnosing urinary tract infections (UTIs) and other kidney-related conditions.

Non-HDL cholesterol is a measure of all cholesterol types that can contribute to arterial plaque buildup, including LDL (low-density lipoprotein), VLDL (very low-density lipoprotein), and other atherogenic lipid particles. It is calculated by subtracting HDL (high-density lipoprotein), or "good" cholesterol, from total cholesterol. Non-HDL cholesterol is considered a more comprehensive indicator of cardiovascular risk than LDL cholesterol alone, as it reflects all harmful cholesterol particles.

Halibut intolerance is a condition where individuals have trouble digesting halibut, a flatfish commonly enjoyed as a seafood delicacy. It can cause gastrointestinal discomfort and is different from a halibut allergy, which triggers an immune system response and can lead to more severe symptoms. People with halibut intolerance usually experience digestive problems after consuming halibut or dishes made with it.

Urinary nitrates are chemical compounds usually absent or present only in trace amounts in urine. Their presence can indicate a bacterial infection, such as a urinary tract infection (UTI), because certain bacteria can convert urinary nitrite into nitrate. Nitrate testing is a common diagnostic tool for detecting UTIs.

Catnip (Nepeta cataria) is a herbaceous plant from the mint family, best known for its stimulating effects on cats. While not typically consumed by humans, some people may experience catnip intolerance — a sensitivity to its compounds that can cause digestive discomfort. This is different from a catnip allergy, which involves an immune response and can lead to more severe symptoms.

Carrot allergy is an allergic reaction caused by specific proteins found in carrots. Although rare, it can affect individuals sensitive to certain plant-based foods. It is commonly associated with Oral Allergy Syndrome (OAS), especially in people allergic to birch or mugwort pollen because of cross-reactive proteins.

KMO (Kynurenine 3-monooxygenase) is an enzyme that plays a key role in the kynurenine pathway, responsible for metabolizing the amino acid tryptophan. It helps regulate the balance of metabolites within this pathway, influencing processes that can affect brain health. KMO activity has been linked to neurological conditions such as Alzheimer’s disease, Huntington’s disease, and schizophrenia.

Urobilinogen in urine is a byproduct of red blood cell breakdown, formed in the intestines from bilirubin and excreted in the urine. It is normally present in low concentrations and serves as an indicator of liver function and health. Abnormally high or low levels may suggest liver disease or blood-related conditions.

Pancreatic elastase is an enzyme produced by the pancreas that plays a crucial role in protein digestion. Measuring its levels in stool can offer valuable insights into pancreatic function. Because the enzyme remains stable in fecal matter, it serves as a dependable marker for evaluating the exocrine function of the pancreas, particularly in diagnosing pancreatic insufficiency.

Allergies to seafood such as plaice, anchovy, and Alaska pollock occur when the immune system reacts to specific proteins in these fish. These reactions can cause a range of symptoms and may significantly impact diet and lifestyle. Understanding the triggers, symptoms, and management strategies is important for those living with these allergies.

Dientamoeba fragilis is a single-celled parasite that lives in the human gastrointestinal tract. It is associated with dientamoebiasis, a condition that can cause a range of digestive symptoms. Its exact method of transmission and role in causing disease are still being studied.

Cucumber intolerance is a condition where the body struggles to digest cucumber, often causing gastrointestinal discomfort. Unlike a cucumber allergy, which triggers an immune response and may lead to more severe reactions, cucumber intolerance usually results in digestive symptoms after eating cucumber.

ATXN1 (Ataxin 1): ATXN1 is a gene that encodes the ataxin-1 protein, which is involved in neuronal function. Mutations in ATXN1, particularly those with expanded CAG repeats, cause spinocerebellar ataxia type 1 (SCA1)—a neurodegenerative disorder characterized by progressive loss of motor coordination and balance. Researching ATXN1 is crucial for understanding SCA1 and developing potential treatments for related neurological conditions.

AMBRA1 (Autophagy and Beclin 1 Regulator 1): AMBRA1 is a crucial protein that regulates autophagy, the process by which cells break down and recycle their components. It promotes cell survival under stress by collaborating with BECN1 (Beclin 1) to initiate autophagosome formation. Proper AMBRA1 function is vital for cellular homeostasis, and its dysfunction has been linked to developmental disorders and neurodegenerative diseases.

ALX4 (ALX Homeobox 4): ALX4 is a transcription factor that plays a crucial role in the development of the skull and limbs. Mutations in this gene are associated with craniofacial malformations and skeletal abnormalities, highlighting its significance in bone formation and morphogenesis.

ALDH1A2 (Aldehyde Dehydrogenase 1 Family Member A2): ALDH1A2 is an enzyme in the aldehyde dehydrogenase family that catalyzes the oxidation of retinaldehyde to retinoic acid, the active form of vitamin A. This conversion is essential for developmental processes such as embryogenesis, tissue patterning, and organ formation, as it regulates gene expression and cell differentiation through retinoic acid signaling. ALDH1A2 is highly expressed in developing tissues, including limb buds, the central nervous system, and sensory organs.

Alaska pollock intolerance is a condition where individuals have trouble digesting Alaska pollock, a type of fish, causing gastrointestinal discomfort. Unlike an allergy to Alaska pollock, which triggers an immune system response and can lead to more severe symptoms, intolerance usually results in digestive problems after eating it.

Chlamydia is a common sexually transmitted infection (STI) caused by the bacterium Chlamydia trachomatis. It can affect both men and women and may cause serious, lasting damage to a woman’s reproductive system, increasing the risk of infertility. In some cases, it can also lead to a potentially life-threatening ectopic pregnancy, where the pregnancy develops outside the uterus.

Anti-Müllerian Hormone (AMH) is a hormone produced by the ovaries that indicates a woman’s ovarian reserve, reflecting the number of eggs remaining. It is commonly used to assess fertility potential and is an important marker in reproductive medicine.

AHCY: Encodes the enzyme adenosylhomocysteinase, which plays a key role in converting S-adenosylhomocysteine to homocysteine, an essential step in the body's methylation processes and detoxification.

Holotranscobalamin (holoTC), also known as active vitamin B12, is the form of vitamin B12 bound to transcobalamin, a transport protein in the blood. It is the only form that can be absorbed by cells through receptor-mediated endocytosis, making it directly available for cellular functions. Measuring holoTC provides a more accurate indication of recent vitamin B12 status than total vitamin B12, as it reflects the fraction that is immediately available for use by the body.

Flaxseed intolerance is a condition that reflects difficulty in digesting flaxseeds, small seeds valued for their rich nutrition and health benefits. It primarily affects the gastrointestinal tract, causing discomfort after consumption. Unlike a flaxseed allergy, which triggers an immune response and can be more severe, flaxseed intolerance mainly results in digestive symptoms when flaxseeds or flaxseed-containing foods are eaten.

Rucola (arugula/rocket) is a leafy green vegetable known for its distinctive peppery flavor and is commonly used in salads, sandwiches, and as a garnish. While generally well tolerated, some individuals may experience arugula intolerance, which can cause discomfort when consuming it.

Rosemary intolerance is a condition characterized by the body’s inability to properly tolerate rosemary, a fragrant and aromatic herb widely used for its distinctive flavor and aroma. While rosemary is commonly enjoyed in many dishes, individuals with this intolerance may experience discomfort or adverse reactions when consuming it.

Apple allergy is an allergic reaction to proteins found in apples. It's commonly associated with Oral Allergy Syndrome (OAS), particularly in individuals who are also allergic to birch pollen, as the proteins in apples can cross-react with birch pollen. Reactions can range from mild to severe, although severe reactions are less common with apple allergies....

Tyrosine boosts brain function and mood. This amino acid helps make neurotransmitters like dopamine, affecting mood and concentration. Found in cheese, soy products, fish, and poultry, tyrosine is key for mental alertness and emotional health. It's important for stress response and thyroid function....

Vanillylmandelic acid (VMA) is a metabolite resulting from the breakdown of catecholamines like adrenaline, noradrenaline, and dopamine. It serves as a clinical marker for assessing catecholamine activity. VMA levels are typically measured in urine and can be influenced by certain foods and medications....

NMRK1 (Nicotinamide Riboside Kinase 1): NMRK1 is an enzyme that catalyzes the phosphorylation of nicotinamide riboside to nicotinamide mononucleotide, a key step in the NAD+ biosynthesis pathway. NAD+ is essential for energy metabolism, DNA repair, and cellular signaling. NMRK1's role in NAD+ biosynthesis makes it important for maintaining cellular energy balance and genomic stability, with implications for aging, metabolic disorders, and diseases associated with NAD+ depletion....

Eicosapentaenoic acid (EPA) is a critical Omega-3 fatty acid primarily found in fish and seafood. Known for its anti-inflammatory properties, EPA plays a vital role in cardiovascular health and is crucial for maintaining a healthy balance of bodily functions....

JAK2 (Janus Kinase 2): JAK2 is a gene encoding a kinase enzyme that is part of the Janus kinase (JAK) family. JAK2 is involved in cytokine signaling pathways and is crucial for the activation of immune and hematopoietic cells. Mutations in JAK2 are associated with blood disorders such as polycythemia vera and myeloproliferative neoplasms....

TRPM6 (Transient Receptor Potential Cation Channel Subfamily M Member 6): TRPM6 is a channel involved in magnesium absorption and homeostasis. It is essential for maintaining proper magnesium balance in the body, and mutations in TRPM6 can lead to hypomagnesemia with secondary hypocalcemia, a condition characterized by low levels of magnesium and calcium in the blood....

BCL2 (B-Cell Lymphoma 2): BCL2 is a gene that encodes a protein involved in regulating apoptosis, a process of programmed cell death. BCL2 proteins play a crucial role in maintaining the balance between cell survival and cell death. Dysregulation of BCL2 is implicated in cancer and various diseases....

NR4A2 (Nuclear Receptor Subfamily 4 Group A Member 2): NR4A2, also known as Nurr1, is a transcription factor essential for the development and maintenance of dopaminergic neurons in the brain. It's involved in neuroprotection and has been studied in relation to Parkinson's disease and other neurodegenerative disorders....

Mycoplasma, particularly Mycoplasma hominis (MH), is a type of bacteria that can be transmitted through sexual contact, although it is not strictly classified as a sexually transmitted infection (STI). It is one of several species of Mycoplasma that affect humans and can inhabit the genital and respiratory tracts. While often asymptomatic, it can cause health problems, particularly in the genitourinary tract....

TRMO (tRNA Methyltransferase 10 Homolog A): TRMO is a gene involved in tRNA modification. It encodes an enzyme responsible for methylating specific nucleotides in tRNA molecules. tRNA modifications are essential for accurate protein synthesis during translation....

BHMT (Betaine-Homocysteine S-Methyltransferase): BHMT plays a crucial role in the metabolism of homocysteine, a process important for cardiovascular and neurological health. It catalyzes the conversion of homocysteine to methionine, using betaine as a methyl donor. Dysregulation of BHMT can lead to elevated homocysteine levels, associated with cardiovascular diseases and other health issues....

ARAP2 (ArfGAP With RhoGAP Domain, Ankyrin Repeat, and PH Domain 2): ARAP2 is involved in cell signaling pathways, acting as a GTPase-activating protein for Arf and Rho family members. It's important for cell migration and cytoskeletal organization, with potential implications in cancer metastasis and cellular morphology....

ALDH7A1 (Aldehyde Dehydrogenase 7 Family Member A1): ALDH7A1 is involved in the metabolism of aldehydes and is essential for the detoxification of pyridoxal-5'-phosphate, a form of vitamin B6. Deficiency in ALDH7A1 leads to pyridoxine-dependent epilepsy, a condition where seizures are caused by an abnormality in lysine metabolism and are responsive to vitamin B6 treatment....

ACKR2 (Atypical Chemokine Receptor 2): Also known as D6, ACKR2 is an atypical chemokine receptor that does not signal in the conventional manner but instead acts to scavenge chemokines from the environment. This function is critical in regulating inflammatory responses and maintaining immune homeostasis. ACKR2's role in clearing chemokines makes it important in controlling the spread of inflammation and has been implicated in various inflammatory diseases, including asthma, psoriasis, and cancer....

TRIM63 (Tripartite Motif Containing 63): TRIM63, also known as MuRF1, is involved in muscle protein degradation, particularly during muscle atrophy. It targets specific muscle proteins for ubiquitination and subsequent degradation in the proteasome. TRIM63 is important in conditions of muscle wasting such as cachexia, sarcopenia, and heart failure. Understanding its role could aid in developing therapies for muscle-wasting diseases....

TRMT6, also known as tRNA methyltransferase 6 homolog, is an enzyme involved in the post-transcriptional modification of transfer RNA (tRNA). Specifically, TRMT6 belongs to the class I-like SAM (S-adenosylmethionine)-dependent methyltransferase superfamily and catalyzes the methylation of specific nucleotides within tRNA molecules. One of the primary functions of TRMT6 is its role in the modification of adenosine residues at the wobble position of certain tRNA molecules. This modification is crucial for ensuring accurate and efficient translation of mRNA into protein during the process of protein synthesis. Methylation at the wobble position of tRNA helps stabilize codon-anticodon interactions and contributes to the fidelity...

TRIM37 (Tripartite Motif Containing 37): TRIM37 is a gene encoding a protein with E3 ubiquitin ligase activity, involved in protein degradation. It has been implicated in the Mulibrey nanism, a rare growth disorder. The study of TRIM37 is important in understanding growth and developmental disorders and the ubiquitin-proteasome system....

TRIM33 (Tripartite Motif Containing 33): TRIM33 is an E3 ubiquitin ligase involved in transcriptional regulation and DNA repair. It plays a role in chromatin remodeling and has been implicated in the regulation of stem cell differentiation and in the suppression of tumorigenesis....